Microsorum scolopendra extracts: as new bioactive agents

Abstract

Microsorum scolopendia (MS), grows on the Chilean island of Rapa Nui, is a fern used to treat several diseases. The aim of this study was to perform a characterization of compound and to evaluate biological properties of MS extracts. The compound identity was analyzed using reversed-phase high-performance liquid chromatography method coupled to mass spectrometry. The radical scavenging and anti-inflammatory activities were evaluated for DPPH, ORAC, and COX inhibition activity assay. A 46% of phenolic compound were founded in rhizome and several important flavonoids such as protocatechic acid 4-O-glucoside. MS extract showed antioxidant properties and anti-inflammatory selective property against COX-2 enzyme. MS extract could have a therapeutic potential to treat several inflammatory diseases.